Angelica Sinensis Extract, Donggui Extract, Ferulic Acid, Z-Ligustilide, Blood-Tonifying, Blood-Circulating, Menstrual-Regulating, Liver-Protecting, Antioxidant, Pharmaceutical Grade
1. Product Description & Key ParametersAngelica Sinensis Extract is a natural botanical extract derived from the dried roots of Angelica sinensis (Oliv.) Diels, a perennial herb belonging to the Apiaceae family, commonly known as "Donggui" in traditional Chinese medicine and hailed as the "sacred medicine for blood" with a reputation of "nine out of ten prescriptions contain Angelica"[4]. It is native to China, mainly distributed in Gansu, Yunnan, Sichuan, Shaanxi and Hubei provinces, with Gansu Min County being the core producing area, where the unique alpine and cool climate and fertile sandy soil provide ideal growing conditions for Angelica sinensis[2][4]. With a long history of medicinal and edible application, it is valued for its effects of tonifying blood, activating blood circulation, regulating menstruation, relieving pain, moistening intestines and relaxing bowels[1][4]. The extract is produced through advanced extraction processes such as supercritical CO extraction, ethanol reflux extraction, steam distillation and ultrasound-assisted extraction, which effectively retain the bioactive components such as Z-ligustilide (the main active component), ferulic acid, Angelica polysaccharides and volatile oils without damaging their activity[3][5][6]. The final product is a brown to dark brown fine powder with a characteristic herbal aroma, good flowability, no visible impurities and uniform particle size, consistent with the typical appearance of Angelica Sinensis Extract. It has good solubility in ethanol and hot water, and moderate solubility in cold water, which is conducive to its application in various water-based and alcohol-based formulations[1][6].Core Parameters:
- Assay Ratio: Customizable (5:1, 10:1, 20:1, 50:1), standard ratio 10:1; also available in 1%, 3%, 5% concentrated specifications of total ferulic acid and Z-ligustilide, and high-purity specifications (ferulic acid HPLC ≥98%, Z-ligustilide HPLC ≥98%)[1][3]
- Active Ingredients: Ferulic Acid ≥3.0% (standard ratio), Z-Ligustilide ≥5.0% (standard ratio), Angelica Polysaccharides ≥8.0%, Total Volatile Oils ≥1.0%, Flavonoids ≥2.0%, Amino Acids ≥4.0%, Trace Elements (Fe, Zn, Mg) ≥0.3%[1][2][3]
- Loss on Drying: ≤0.5% (high-purity ferulic acid/Z-ligustilide); ≤3.0% (standard extract)[1]
- Ash Content: ≤0.1% (high-purity ferulic acid/Z-ligustilide); ≤5.0% (standard extract)[1]
- Heavy Metals: ≤10ppm (Pb ≤1.0ppm, Cd ≤0.3ppm, As ≤1.0ppm, Hg ≤0.1ppm)[1]
- Microbial Limits: Total Aerobic Microbes ≤1000cfu/g, Yeast & Mold ≤100cfu/g, Coliforms: Negative, Salmonella: Negative (25g sample)
- Solubility: ≥90% soluble in ethanol (25ºC, 70% v/v); ≥80% soluble in hot water (60ºC, 10% w/v); ≥50% soluble in cold water (25ºC, 10% w/v); slightly soluble in petroleum ether[1][6]
- Particle Size: 80-100 mesh (standard), customizable 60-120 mesh (fine powder specifications available for pharmaceutical, health care and food applications)[1]
- pH Value: 5.5-7.5 (1% w/v aqueous solution)
- Molecular Weight: 194.18 Da (ferulic acid, chemical formula CHO, CAS No.: 1135-24-6); 202.25 Da (Z-ligustilide, CAS No.: 4431-01-0); 1000-5000 Da (Angelica polysaccharides)[1][3]
- Shelf Life: 24 months (sealed, protected from light, moisture and high temperature; stored in a dry and low-temperature environment to avoid oxidation and degradation of active components)[1]
- Packaging: 1kg/Aluminum Foil Bag, 5kg/Carton, 25kg/Fiber Drum (double plastic bag inside); small specifications (1g, 10g, 50g) available for high-purity samples and laboratory use[1]
- Certifications: ISO 9001, GMP, HACCP, Halal, Kosher, FDA (Food Grade, Pharmaceutical Grade), HPLC fingerprint authentication[1][2]
- Detection Method: TLC (Thin Layer Chromatography), HPLC (for ferulic acid and Z-ligustilide content, chromatographic column C18, mobile phase acetonitrile-0.1% phosphoric acid water); GC-MS for volatile oil component identification; UV-Vis for total flavonoids and polysaccharides detection[3][1]Angelica Sinensis Extract is a high-value natural botanical extract, rich in unique bioactive substances and nutrients, mainly including Z-ligustilide (the core active component), ferulic acid, Angelica polysaccharides, volatile oils, flavonoids, trace elements (Fe, Zn, Mg) and amino acids[1][2][3]. These components are the key material basis for its blood-tonifying, blood-circulating, menstrual-regulating, liver-protecting and antioxidant activities. The product complies with international standards of food grade, cosmetic grade and pharmaceutical grade, and its quality is strictly controlled through scientific detection methods to ensure batch consistency and efficacy stability[1][2]. It has good safety, no obvious toxic and side effects, but pregnant women, people with excessive menstrual flow and those with diarrhea due to spleen deficiency should use it with caution under the guidance of professionals[1][4].2. Features - Natural and High-Quality Sourcing: Sourced from high-quality Angelica sinensis grown in pollution-free alpine environments (main producing area: Min County, Gansu of China), the raw materials are strictly selected-healthy, intact dried roots with strong herbal aroma are cleaned, sliced and processed to ensure no impurities[2][4]. The raw materials are harvested in autumn, dried by low-temperature baking or smoke curing to retain the active components (especially heat-sensitive Z-ligustilide and ferulic acid) to the greatest extent, ensuring the high nutritional value and efficacy of the extract[4][5]. No artificial colors, flavors or preservatives are added during the extraction process, making it a safe and natural botanical ingredient with extensive application value[1][6].
- Standardized Parameters and High Purity: Strictly controlled parameters (active ingredient content, solubility, particle size, etc.) ensure batch consistency. Precise supercritical CO extraction and purification technologies concentrate core active components such as Z-ligustilide and ferulic acid, with high-purity specifications reaching HPLC ≥98%[3][5]. The content of active components is stable, and the scientific ratio of active substances ensures comprehensive efficacy, which can better exert its functional effects, especially in blood-tonifying, blood-circulating and menstrual-regulating activities[1][4]. The detection methods are scientific and accurate, and HPLC fingerprint authentication and GC-MS component identification ensure the authenticity and reliability of product quality[3][1].
- Good Compatibility and Solubility: Consistent with parameter standards, it has good solubility in ethanol and hot water, compatible with most ingredients in pharmaceuticals, health products and food (both water-based and alcohol-based ingredients) without obvious incompatibility[1][6]. It can be flexibly added to various product formulations (such as powders, capsules, oral liquids, health teas, tonics) without affecting the original texture, color and efficacy of the products. Its good compatibility also ensures uniform dispersion in formulations, fully exerting its functional effects, which is suitable for the development of various dosage forms such as oral pharmaceutical preparations and health care products[1][4].
- Stable Physical and Chemical Properties: Under specified storage conditions (sealed, light-proof, low-temperature), it maintains good stability, with no significant changes in the content and activity of active ingredients (especially Z-ligustilide and ferulic acid). It has stable physical and chemical properties such as melting point and density, but is easy to oxidize when exposed to light and high temperature, so it needs strict storage conditions[1][3]. It is easy to store and transport when following the storage requirements, meeting the storage and transportation requirements of industrial production, especially for pharmaceutical and health care applications[1][2].
- Multi-functional and Versatile: It integrates multiple biological activities such as blood-tonifying, blood-circulating, menstrual-regulating, relieving pain, liver-protecting, antioxidant and immune-regulating, with prominent effects on tonifying blood, activating blood circulation, regulating menstruation and protecting liver health[1][2][4]. It also has effects on anti-inflammatory, anti-tumor, anti-thrombotic and intestinal moistening, with strong adaptability in multiple fields and a wide range of application scenarios[1][2]. It is suitable for clinical medical auxiliary, daily health care and cosmetic formulation, and can also be used as a natural food additive and health care ingredient[1][6].
3. Functions - Blood-Tonifying and Nourishing: As a classic blood-tonifying botanical extract, its core active components Angelica polysaccharides and ferulic acid can significantly promote the production of hemoglobin and red blood cells, improve anemia symptoms such as sallow complexion, dizziness, palpitations, fatigue and pale lips and nails[1][4]. It can tonify blood and nourish qi, regulate the balance of qi and blood in the body, and is suitable for people with blood deficiency and qi deficiency[1][4].
- Blood-Circulating and Stasis-Removing: Z-ligustilide and ferulic acid in the extract can dilate blood vessels, improve blood circulation, reduce blood viscosity, inhibit platelet aggregation and prevent thrombosis[1][2]. It can activate blood circulation and remove blood stasis, relieve symptoms such as blood stasis and pain, and has a good auxiliary effect on traumatic injuries, rheumatic arthralgia and blood stasis-type diseases[1][4].
- Menstrual-Regulating and Pain-Relieving: It is a classic medicinal ingredient for regulating women's menstruation, which can regulate menstrual cycles, relieve menstrual irregularities, dysmenorrhea, amenorrhea and other symptoms caused by blood deficiency and blood stasis[1][4]. It can warm the meridians and relieve pain, and has a significant improvement effect on cold abdominal pain and dysmenorrhea caused by cold in the uterus, which is known as the "key medicine for women's diseases"[4][6].
- Liver-Protecting: It has a good protective effect on the liver, can regulate immune function, improve non-alcoholic fatty liver by restoring the expression of liver estrogen-related receptor α, inhibit liver fibrosis, and reduce liver cell damage caused by various factors[1][2]. It can also promote liver metabolism, assist in relieving liver discomfort, and have an auxiliary improvement effect on chronic liver diseases[1][2].
- Antioxidant: Ferulic acid and flavonoids in the extract have strong antioxidant activity, which can effectively scavenge DPPH, ABTS+ and other free radicals in the body, inhibit lipid peroxidation, protect cell membranes from free radical damage, delay the aging process of the body, and improve memory and cognitive function in the elderly[1][2].
- Additional Functions: It has anti-inflammatory activity, and its active components can relax tracheal smooth muscle, resist bronchial asthma caused by histamine and acetylcholine, and have a certain relieving effect on respiratory inflammation[1]. It also has anti-tumor potential, can inhibit the proliferation of various cancer cells (such as glioblastoma, colorectal cancer), induce cancer cell apoptosis, and can be used as an auxiliary ingredient in anti-tumor health care products and drugs[2]. In addition, it has the effect of moistening intestines and relaxing bowels, which is suitable for constipation caused by blood deficiency and intestinal dryness, especially for the elderly, post-partum women and people with insufficient qi and blood[4][6].
4. Application Fields - Pharmaceutical Industry: As a core raw material, it is mainly used in the development of drugs for blood-tonifying, blood-circulating, menstrual-regulating, pain-relieving and liver-protecting. It is also used in Chinese patent medicines and Western medicines for the auxiliary treatment of anemia, menstrual disorders, dysmenorrhea, amenorrhea, chronic liver diseases, rheumatic arthralgia and traumatic injuries[1][4]. Its high-purity ferulic acid and Z-ligustilide are widely used in the research and development of drugs for blood circulation improvement and liver protection, with broad application prospects in the field of medicine[1][3].
- Healthcare Products Industry: Used as a functional ingredient in oral health supplements such as capsules, tablets, oral liquids, health teas and tonics, focusing on functions such as blood-tonifying, blood-circulating, menstrual-regulating, liver-protecting and anti-aging[1][4]. It is especially suitable for women with menstrual health needs, people with blood deficiency and qi deficiency, middle-aged and elderly people with liver health needs, and those who need daily blood nourishment and anti-aging care. It should be noted that pregnant women and people with excessive menstrual flow should use it with caution[1][4].
- Food Industry: Used as a natural food additive and functional ingredient in functional beverages, health teas, nutritional snacks, edible powders and health tonics[1][6]. Its unique herbal flavor can enrich the flavor of food, and its rich nutritional components and functional activities can increase the health value of food, which is suitable for the development of functional health foods focusing on blood-tonifying and nourishing[1][4].
- Cosmetics & Daily Chemical Industry: Applied to blood-circulating, nourishing and repairing skin care products such as facial creams, masks, serums and lotions[1][6]. Its blood-circulating and antioxidant properties can improve skin microcirculation, relieve skin dullness and dryness, nourish skin, reduce pigmentation, and repair damaged skin barrier[1][6]. It can also be added to hair care products to nourish hair, promote hair growth and enhance hair toughness[1].
- Other Fields: Used as a natural functional ingredient in feed additives to improve animal growth performance and enhance animal immunity[1]. It can also be used in the research and development of pharmaceutical auxiliary materials and health care products, and has broad application prospects in the fields of agriculture, biomedicine and life science research[1][2]. In addition, it can be developed into characteristic health products combining traditional Chinese medicine with modern processing technology, meeting the market demand for natural and safe blood-tonifying and nourishing ingredients[1][4].
About Us:
Fufeng Sinuote Biotechnology Co., Ltd is strategically positioned in the bustling Jiangba Science and Technology Industrial Park, Fufeng County, Baoji Province, China. As trailblazers in the research, development, and promotion of superior plant extracts, we hold an esteemed portfolio of qualifications, including SC, export license, HACCP, ISO22000, and ISO9001. Recognized as a high-tech enterprise, we produce over 600 varieties of extracts, supported by a vast cultivation base exceeding 1,000,000 square meters in Gansu & Ningxia Province. Our decade-long expertise guarantees exceptional plant quality and outstanding extract powder. We enjoy a celebrated reputation, receiving acclaim from clients worldwide. Plant Extract industry for over ten years, and we have received positive feedback from our numerous clients in many countries.
Product Categories : Plant Extract
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