Resveratrol Extract, Trans-Resveratrol, Natural Resveratrol, Polyphenol Extract, Antioxidant, Anti-Aging, Cardiovascular Protection, Anti-Inflammatory, Anti-Tumor, Food Grade 1. Product Description & Key ParametersResveratrol Extract is a natural polyphenolic extract derived from the skins, seeds and roots of plants such as Vitis vinifera (grape), Arachis hypogaea (peanut), and Vaccinium corymbosum (blueberry), belonging to the stilbene class of polyphenolic compounds[1][3]. It is a plant antitoxin synthesized by plants when subjected to UV radiation, mechanical damage or fungal infection, and has been widely concerned for its excellent biological activities[1][6]. The extract is mainly produced in China (Gansu, Qinghai, Ningxia), the Netherlands, the United States and other regions, with China accounting for half of the global output[4]. It is produced through advanced ethanol reflux extraction, supercritical CO extraction, ultrasound-assisted extraction, purification, concentration and spray-drying processes, which effectively retain the bioactive components such as trans-resveratrol (the main active form), cis-resveratrol and resveratrol glycosides without damaging their activity[1][4]. The final product is a white to off-white or pale yellow fine powder with a slight characteristic odor, good flowability, no visible impurities and uniform particle size, consistent with the typical appearance of resveratrol extract. It has good solubility in ethanol and hot water, and moderate solubility in cold water, which is conducive to its application in various water-based and alcohol-based formulations[2][4].Core Parameters:
- Assay Ratio: Customizable (5:1, 10:1, 20:1, 50:1), standard ratio 10:1; also available in 5%, 10%, 20%, 50% concentrated specifications of total resveratrol, and high-purity trans-resveratrol specifications (HPLC ≥98%-99%)[2][4]
- Active Ingredients: Trans-Resveratrol ≥98% (for high-purity specification), Total Resveratrol (trans + cis) ≥5.0% (standard ratio), Resveratrol Glycosides ≥2.0%, Total Polyphenols ≥15.0%, Flavonoids ≥3.0%, Vitamin E ≥0.5%, Trace Elements (Zn, Se, Mg) ≥0.3%[1][2][3]
- Loss on Drying: ≤0.5% (high-purity trans-resveratrol); ≤3.0% (standard extract)[2]
- Ash Content: ≤0.1% (high-purity trans-resveratrol); ≤5.0% (standard extract)[2]
- Heavy Metals: ≤10ppm (Pb ≤1.0ppm, Cd ≤0.3ppm, As ≤1.0ppm, Hg ≤0.1ppm)[2]
- Microbial Limits: Total Aerobic Microbes ≤1000cfu/g, Yeast & Mold ≤100cfu/g, Coliforms: Negative, Salmonella: Negative (25g sample)
- Solubility: ≥90% soluble in ethanol (25ºC, 70% v/v); ≥80% soluble in hot water (60ºC, 10% w/v); ≥50% soluble in cold water (25ºC, 10% w/v); slightly soluble in petroleum ether[2][4]
- Particle Size: 80-100 mesh (standard), customizable 60-120 mesh (fine powder specifications available for food, cosmetic and pharmaceutical applications)[4]
- pH Value: 5.0-7.0 (1% w/v aqueous solution)
- Molecular Weight: 228.25 Da (trans-resveratrol, chemical formula C14H12O3, CAS No.: 501-36-0), small molecule structure easy to be absorbed by the human body[2][5]
- Shelf Life: 24 months (sealed, protected from light, moisture and high temperature; stored in a dry and low-temperature environment to avoid oxidation and degradation)[4]
- Packaging: 1kg/Aluminum Foil Bag, 5kg/Carton, 25kg/Fiber Drum (double plastic bag inside); small specifications (1g, 10g, 50g) available for high-purity samples and laboratory use[4]
- Certifications: ISO 9001, GMP, HACCP, Halal, Kosher, FDA (Food Grade, Pharmaceutical Grade), GRAS certified, HPLC fingerprint authentication[2][4]
- Detection Method: TLC (Thin Layer Chromatography), HPLC (for trans-resveratrol, cis-resveratrol and total resveratrol content, chromatographic column C18, mobile phase acetonitrile-water); UV-Vis for total polyphenols and flavonoids detection[2][3]Resveratrol Extract is a high-value natural polyphenolic extract, rich in unique bioactive substances and nutrients, mainly including trans-resveratrol (the most biologically active isomer), cis-resveratrol, resveratrol glycosides, total polyphenols and flavonoids[1][2][3]. These components are the key material basis for its antioxidant, anti-aging, cardiovascular protection, anti-inflammatory and anti-tumor activities. The product complies with international standards of food grade, cosmetic grade and pharmaceutical grade, with natural source accounting for 80% of the global market, and its quality is strictly controlled through scientific detection methods to ensure batch consistency and efficacy stability[4]. It has good safety, no obvious toxic and side effects, but long-term excessive use may cause mild gastrointestinal discomfort[1].2. Features - Natural and High-Quality Sourcing: Sourced from high-quality plants (mainly grape skins and seeds) grown in pollution-free environments (main producing areas: Gansu, Qinghai, Ningxia of China), the raw materials are strictly selected-fresh, intact plant parts with high resveratrol content are cleaned, dried and processed to ensure no impurities[4][6]. The raw materials are cultivated in a standardized manner, and the extraction process adopts low-temperature and supercritical extraction technologies to retain the natural bioactive components (especially heat-sensitive resveratrol isomers) to the greatest extent, ensuring the high nutritional value and efficacy of the extract[4]. No artificial colors, flavors or preservatives are added during the extraction process, making it a safe and natural polyphenolic ingredient with extensive application value[1][4].
- Standardized Parameters and High Purity: Strictly controlled parameters (active ingredient content, isomer ratio, solubility, etc.) ensure batch consistency. Precise supercritical extraction and purification technologies concentrate core active components such as trans-resveratrol, with high-purity specifications reaching HPLC ≥98%-99%[2][4]. The content of active components is stable, and the scientific ratio of resveratrol isomers ensures comprehensive efficacy, which can better exert its functional effects, especially in antioxidant, anti-aging and cardiovascular protection activities[1][3]. The detection methods are scientific and accurate, and HPLC fingerprint authentication ensures the authenticity and reliability of product quality[2][4].
- Good Compatibility and Solubility: Consistent with parameter standards, it has good solubility in ethanol and hot water, compatible with most ingredients in food, health products, pharmaceuticals and cosmetics (both water-based and alcohol-based ingredients) without obvious incompatibility[2][4]. It can be flexibly added to various product formulations (such as powders, capsules, oral liquids, facial masks, serums, health wines) without affecting the original texture, color and efficacy of the products. Its good compatibility also ensures uniform dispersion in formulations, fully exerting its functional effects, which is suitable for the development of various dosage forms such as oral health products and high-end skin care products[1][4].
- Stable Physical and Chemical Properties: Under specified storage conditions (sealed, light-proof, low-temperature), it maintains good stability, with no significant changes in the content and activity of active ingredients (especially trans-resveratrol). It has stable physical and chemical properties such as melting point and density, but is easy to oxidize when exposed to light and high temperature, so it needs strict storage conditions[2][4]. It is easy to store and transport when following the storage requirements, meeting the storage and transportation requirements of industrial production, especially for food and cosmetic applications.
- Multi-functional and Versatile: It integrates multiple biological activities such as antioxidant, anti-aging, cardiovascular protection, anti-inflammatory, anti-tumor and estrogen regulation, with prominent effects on scavenging free radicals, delaying aging and protecting cardiovascular health[1][3]. It also has effects on antibacterial, immune regulation and neuroprotective, with strong adaptability in multiple fields and a wide range of application scenarios[1][3][6]. It is suitable for both daily health care and pharmaceutical auxiliary, and can also be used as a natural food additive and high-end cosmetic ingredient[4][6].
3. Functions - Powerful Antioxidant: As a high-efficiency natural antioxidant, its core active component trans-resveratrol can effectively scavenge DPPH, ABTS+ and other free radicals in the body, inhibit the production of reactive oxygen species (ROS), and reduce oxidative damage to cells and tissues[1]. It can also inhibit lipid peroxidation, protect cell membranes from free radical damage, enhance the activity of antioxidant enzymes in the body, and delay the aging process of the body, which is widely used in health care products and cosmetics[1][6].
- Anti-Aging: Trans-resveratrol can activate sirtuin (a protein that repairs chromosome health), maintain the integrity of chromosomes, delay cellular aging, and improve skin firmness and elasticity[1]. It can also promote collagen synthesis, reduce wrinkles, relieve skin dullness and dryness, and achieve the effect of skin anti-aging, which is suitable for people who need anti-aging care[1][6].
- Cardiovascular Protection: It can inhibit the abnormal expression of tissue factor (TF) and cytoplasm in vascular cells, regulate the function of vascular endothelial cells, and inhibit the formation of thromboxane[1]. It can also regulate lipid metabolism, reduce serum lipid content, inhibit cholesterol deposition in the liver, lower the arteriosclerosis index, dilate blood vessels, increase the release of NO and adenosine, and protect chronic ischemic myocardium, which has an auxiliary improvement effect on cardiovascular diseases[1][3].
- Anti-Inflammatory: Resveratrol and its derivatives have obvious anti-inflammatory activity, which can inhibit the production of pro-inflammatory cytokines (such as interleukins 6 and 8), relieve acute and chronic inflammation, and have a good improvement effect on various inflammatory reactions[3][6]. It can also relieve skin inflammation and sensitivity, and has a certain relieving effect on allergic dermatitis[1].
- Anti-Tumor: It has a potential anti-tumor effect, can inhibit the proliferation of various cancer cells (such as lung cancer, liver cancer, pancreatic cancer, colon cancer), induce cancer cell apoptosis and autophagy, block the cancer cell growth cycle, and inhibit cancer cell metastasis[1][3]. It can also regulate immune function, enhance the effect of other anti-tumor drugs, and can be used as an auxiliary ingredient in anti-tumor health care products and drugs[3].
- Additional Functions: It has estrogen regulation effect, whose chemical structure is similar to estradiol, can activate estrogen receptors and play a role in estrogen signal transduction, helping to prevent diseases caused by insufficient estrogen secretion in women after menopause[1]. It also has antibacterial activity, which can inhibit the growth of Pseudomonas aeruginosa, Shigella flexneri and other bacteria, and improve the body's resistance to pathogens[1]. In addition, it has a certain neuroprotective effect, can protect neuronal cells, and has a potential protective effect on neurodegenerative diseases[3].
4. Application Fields - Pharmaceutical Industry: As a core raw material, it is mainly used in the development of drugs for antioxidant, anti-inflammatory, cardiovascular protection and anti-tumor auxiliary. It is also used in pharmaceutical preparations such as oral tablets and capsules for the auxiliary treatment of cardiovascular diseases, inflammatory diseases, tumors and neurodegenerative diseases[1][3]. Its high-purity trans-resveratrol is widely used in the research and development of anti-tumor and anti-aging drugs, with broad application prospects in the field of medicine[2][4].
- Healthcare Products Industry: Used as a functional ingredient in oral health supplements such as capsules, tablets, oral liquids, health teas, health wines and powders, focusing on functions such as antioxidant, anti-aging, cardiovascular protection and immune regulation[1][4]. It is especially suitable for middle-aged and elderly people, people with cardiovascular health needs, people with low immunity, and those who need daily anti-aging care. It is one of the most popular functional ingredients in the global health product market, with the United States being the largest consumer market[4].
- Food Industry: Used as a natural food additive and functional ingredient in functional beverages, health wines, nutritional snacks, edible powders and fruit products[4][6]. Its rich polyphenolic components can increase the health value of food, and it can also be added to grape products to enhance the flavor and nutritional value, which is suitable for the development of functional health foods focusing on antioxidant and anti-aging[1][4].
- Cosmetics & Daily Chemical Industry: Applied to anti-aging, moisturizing, firming and repairing high-end skin care products such as facial creams, masks, serums and lotions[1][4]. Its antioxidant and anti-aging properties can relieve skin aging, promote collagen synthesis, improve skin texture, and reduce skin inflammation and sensitivity[1][6]. It can also be added to hair care products to nourish hair, enhance hair toughness and reduce hair loss[4].
- Other Fields: Used as a natural functional ingredient in feed additives to improve animal growth performance and enhance animal immunity[4]. It can also be used in the research and development of pharmaceutical auxiliary materials and food additives, and has broad application prospects in the fields of agriculture, biomedicine and life science research[4][6]. In addition, it can be developed into characteristic health products combining natural plant extracts with modern processing technology, meeting the market demand for natural and safe antioxidant and anti-aging ingredients[1][4].
About Us:
Fufeng Sinuote Biotechnology Co., Ltd is strategically positioned in the bustling Jiangba Science and Technology Industrial Park, Fufeng County, Baoji Province, China. As trailblazers in the research, development, and promotion of superior plant extracts, we hold an esteemed portfolio of qualifications, including SC, export license, HACCP, ISO22000, and ISO9001. Recognized as a high-tech enterprise, we produce over 600 varieties of extracts, supported by a vast cultivation base exceeding 1,000,000 square meters in Gansu & Ningxia Province. Our decade-long expertise guarantees exceptional plant quality and outstanding extract powder. We enjoy a celebrated reputation, receiving acclaim from clients worldwide. Plant Extract industry for over ten years, and we have received positive feedback from our numerous clients in many countries.
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