1. Product Description

Dryopteris Crassirhizoma Extract, commonly known as Guanzhong Extract, is a natural Herbal Extract derived from the dried rhizome and petiole residues of Dryopteris crassirhizoma Nakai, a fern belonging to the Dryopteridaceae family. It is produced through standardized and scientific processes, including raw material sorting, cleaning, crushing, water extraction (or water-ethanol mixed extraction), filtration, vacuum concentration, spray drying, and sieving. The product appears as a brown to dark brown fine powder with a characteristic specific herbal odor, free of artificial colors, flavors, preservatives and harmful impurities. It fully retains the core active ingredients of natural Dryopteris crassirhizoma, such as phloroglucinol derivatives, flavonoids, triterpenes, filixic acid, aspidin and Dryopteris crassirhizoma polysaccharides, which are the key substances for its biological activities. The extract meets the raw material standards of food, health care products, daily chemical and pharmaceutical industries in China, the European Union, the United States and other regions, with high purity, good solubility and stable quality. Optional low-temperature extraction technology can be adopted to maximize the retention of heat-sensitive active ingredients, further improving the product's efficacy and applicability.

2. Key Features

• Premium Raw Material Selection: Selected high-quality, pollution-free dried rhizome and petiole residues of Dryopteris crassirhizoma Nakai, with strict screening to remove impurities, moldy and inferior raw materials, ensuring the naturalness, purity and safety of the product, in line with the standards of traditional Chinese medicinal materials.
• Highly Enriched Active Ingredients: Through advanced extraction and concentration technology, the active ingredients such as phloroglucinol derivatives, flavonoids and Dryopteris crassirhizoma polysaccharides are highly enriched. Common extraction ratios are 10:1, 20:1, 30:1, and high-content specifications (such as total flavonoids ≥5%, ≥10%) can be customized on demand, with stable and reliable efficacy.
• Excellent Solubility and Compatibility: The fine powder (80-100 mesh) has good water solubility and dispersibility, easily soluble in water, ethanol and other common solvents. It can be well compatible with various formulas, suitable for capsule, tablet, oral liquid, skin care products and other production processes, reducing product development difficulty.
• Strict Quality Control: Adopting HPLC/TLC/UV detection methods to strictly control the content of active ingredients, heavy metals, microorganisms and other indicators, referring to the identification and inspection standards of Dryopteris crassirhizoma medicinal materials. It complies with international quality standards, and a complete Certificate of Analysis (COA) can be provided to ensure product safety and compliance.
• Stable Quality and Easy Storage: Sealed in aluminum foil bags and cardboard drums, it can be stored for 24 months in a cool, dry, dark and ventilated environment, not easy to absorb moisture, deteriorate or lose activity, and is convenient for long-term storage and transportation, consistent with the storage requirements of traditional herbal extracts.

3. Main Functions

• Anti-inflammatory and Anti-allergic: It can inhibit the activation of NF-κB signaling pathway, reduce the secretion of inflammatory factors such as IL-6 and TNF-α, alleviate allergic inflammatory responses, and soothe irritated skin and scalp conditions, with significant anti-allergic and anti-inflammatory effects.
• Antibacterial and Antiviral: It has inhibitory effects on a variety of pathogenic bacteria such as Propionibacterium acnes, as well as anti-influenza virus activity, helping the body resist external pathogens and protect the health of the respiratory and skin systems.
• Antioxidant: Dryopteris crassirhizoma polysaccharides and flavonoids in the extract have strong antioxidant activity, which can scavenge DPPH radicals, hydroxyl radicals and superoxide anions, reduce oxidative damage to cells, and delay cell aging.
• Sebum Regulation: It has anti-sebum properties, can regulate the secretion of skin and scalp sebum, reduce skin shine, prevent pore blockage, and is suitable for improving oily skin and scalp problems.
• Anti-tumor and Anti-invasive: It can inhibit the migration and invasion of cancer cells, disturb actin polymerization, reduce the degradation of extracellular matrix, and has potential anti-tumor effects, which can be used as an auxiliary raw material for anti-tumor health products and drugs.
• Immunomodulation: Dryopteris crassirhizoma polysaccharides can enhance the production of nitric oxide in macrophages, activate the activity of immune cells, and improve the body's non-specific immunity, helping to enhance the body's resistance.

4. Application Fields

• Healthcare Product Field: As the core raw material of anti-inflammatory, anti-allergic, antioxidant and immunomodulatory health products, it can be made into capsules, tablets, oral liquids, granules and other products, suitable for sub-healthy groups, people with allergic constitution and people with low immunity.
• Functional Food Field: It can be added to health teas, meal replacement powders, functional beverages and other products to endow products with natural herbal effects, meet consumers' demand for healthy diet, and enrich the functional types of food.
• Daily Chemical & Skin Care Field: Used in oil-controlling, anti-acne, soothing and repairing skin care products, such as toners, masks, lotions, essences and shampoos. It can regulate sebum secretion, soothe irritated skin, improve acne problems, and protect skin and scalp health.
• Pharmaceutical Intermediate Field: As a raw material for anti-inflammatory, antiviral, anti-tumor and immunomodulatory drugs, it is used in the research and development and production of Chinese patent medicines and western medicine preparations to assist in improving drug efficacy, referring to the traditional medicinal value of Dryopteris crassirhizoma.
• Pet Health Product Field: Added to pet food and pet health products, it can enhance pet immunity, soothe pet skin inflammation, regulate pet scalp sebum, and help pets maintain a healthy physical condition.