Garlic Extract, Allicin, Garlic Polysaccharide, Organic Sulfide, Antibacterial, Antioxidant, Lipid-Regulating, Immune-Enhancing, Liver-Protecting, Food Grade
1. Product Description & Key Parameters
Garlic Extract is a natural botanical extract derived from the dried bulbs of Allium sativum L., a perennial herb belonging to the Liliaceae family, commonly known as "garlic" in daily life and recognized as a "natural broad-spectrum antibiotic"[1][4]. It is widely cultivated worldwide, with main producing areas including China (Shandong, Henan, Jiangsu provinces), Egypt, the United States and India, among which China is one of the world's major garlic producers and exporters[2][4]. With a long history of medicinal and edible application, it is valued for its effects of detoxifying and reducing swelling, killing insects, relieving dysentery, regulating blood lipids and enhancing immunity[7]. The extract is produced through advanced extraction processes such as supercritical CO extraction, ethanol reflux extraction, steam distillation and ultrasound-assisted extraction, which effectively retain the bioactive components such as allicin (the main active component), organic sulfides, garlic polysaccharides and flavonoids without damaging their activity[2][4]. The final product is a light yellow to brown fine powder with a characteristic pungent garlic odor, good flowability, no visible impurities and uniform particle size, consistent with the typical appearance of Garlic Extract. It is slightly soluble in water, easily soluble in ethanol, ether and other organic solvents, which is conducive to its application in various alcohol-based and partial water-based formulations[1][2].
Core Parameters:
Assay Ratio: Customizable (5:1, 10:1, 20:1, 50:1), standard ratio 10:1; also available in 1%, 3%, 5% concentrated specifications of total allicin, and high-purity allicin specifications (HPLC ≥98%)[1][2] - Active Ingredients: Allicin ≥5.0% (standard ratio), Organic Sulfides ≥8.0% (including diallyl disulfide, diallyl trisulfide), Garlic Polysaccharides ≥10.0%, Total Flavonoids ≥2.0%, Selenium ≥0.1ppm, Zinc ≥5.0ppm, Amino Acids ≥3.0%[1][2][6][7] - Loss on Drying: ≤0.5% (high-purity allicin); ≤3.0% (standard extract)[2] - Ash Content: ≤0.1% (high-purity allicin); ≤5.0% (standard extract)[2] - Heavy Metals: ≤10ppm (Pb ≤1.0ppm, Cd ≤0.3ppm, As ≤1.0ppm, Hg ≤0.1ppm)[2] - Microbial Limits: Total Aerobic Microbes ≤1000cfu/g, Yeast & Mold ≤100cfu/g, Coliforms: Negative, Salmonella: Negative (25g sample) - Solubility: ≥90% soluble in ethanol (25ºC, 70% v/v); ≥40% soluble in hot water (60ºC, 10% w/v); ≤20% soluble in cold water (25ºC, 10% w/v); easily soluble in ether and petroleum ether[1][2] - Particle Size: 80-100 mesh (standard), customizable 60-120 mesh (fine powder specifications available for pharmaceutical, health care, food and feed applications)[2] - pH Value: 5.0-7.0 (1% w/v aqueous solution) - Molecular Weight: 162.27 Da (allicin, chemical formula CHOS, CAS No.: 539-86-6); 1000-5000 Da (garlic polysaccharides)[1] - Shelf Life: 24 months (sealed, protected from light, moisture and high temperature; stored in a dry and low-temperature environment to avoid oxidation and volatilization of active components)[2] - Packaging: 1kg/Aluminum Foil Bag, 5kg/Carton, 25kg/Fiber Drum (double plastic bag inside); small specifications (1g, 10g, 50g) available for high-purity samples and laboratory use[2] - Certifications: ISO 9001, GMP, HACCP, Halal, Kosher, FDA (Food Grade, Pharmaceutical Grade), GRAS certified, HPLC fingerprint authentication[2][4] - Detection Method: TLC (Thin Layer Chromatography), HPLC (for allicin, diallyl disulfide and diallyl trisulfide content, chromatographic column C18, mobile phase acetonitrile-water); UV-Vis for total flavonoids and garlic polysaccharides detection[1][2]
Garlic Extract is a high-value natural botanical extract, rich in unique bioactive substances and nutrients, mainly including allicin (the core active component), organic sulfides (diallyl disulfide, diallyl trisulfide), garlic polysaccharides, flavonoids, trace elements (selenium, zinc) and amino acids[1][2][6]. These components are the key material basis for its antibacterial, antioxidant, lipid-regulating, immune-enhancing and liver-protecting activities. The product complies with international standards of food grade, cosmetic grade, pharmaceutical grade and feed grade, and its quality is strictly controlled through scientific detection methods to ensure batch consistency and efficacy stability[2][4]. It has good safety, no obvious toxic and side effects, but long-term excessive use may cause mild gastrointestinal discomfort, and people with gastric ulcer and hyperacidity should use it with caution[1][7].
2. Features
- Natural and High-Quality Sourcing: Sourced from high-quality garlic grown in pollution-free environments (main producing areas: Shandong, Henan, Jiangsu of China), the raw materials are strictly selected-fresh, intact bulbs with plump petals and strong garlic aroma are cleaned, dried and processed to ensure no impurities[4][7]. The raw materials are harvested in the appropriate season, dried in a shaded area or by low-temperature baking to retain the active components (especially heat-sensitive allicin) to the greatest extent, ensuring the high nutritional value and efficacy of the extract[2][4]. No artificial colors, flavors or preservatives are added during the extraction process, making it a safe and natural botanical ingredient with extensive application value[1][2].
- Standardized Parameters and High Purity: Strictly controlled parameters (active ingredient content, solubility, particle size, etc.) ensure batch consistency. Precise supercritical CO extraction and purification technologies concentrate core active components such as allicin and organic sulfides, with high-purity allicin specifications reaching HPLC ≥98%[2][4]. The content of active components is stable, and the scientific ratio of active substances ensures comprehensive efficacy, which can better exert its functional effects, especially in antibacterial, antioxidant and lipid-regulating activities[1][7]. The detection methods are scientific and accurate, and HPLC fingerprint authentication ensures the authenticity and reliability of product quality[2][4].
- Good Compatibility and Solubility: Consistent with parameter standards, it has good solubility in ethanol and organic solvents, compatible with most ingredients in pharmaceuticals, health products, food and feed (both alcohol-based and partial water-based ingredients) without obvious incompatibility[1][2]. It can be flexibly added to various product formulations (such as powders, capsules, oral liquids, health wines, feed premixes) without affecting the original texture, color and efficacy of the products. Its good compatibility also ensures uniform dispersion in formulations, fully exerting its functional effects, which is suitable for the development of various dosage forms such as oral pharmaceutical preparations, health care products and feed additives[2][5].
- Stable Physical and Chemical Properties: Under specified storage conditions (sealed, light-proof, low-temperature), it maintains good stability, with no significant changes in the content and activity of active ingredients (especially allicin). It has stable physical and chemical properties such as melting point and density, and can withstand high temperature up to 120ºC in non-strong acid environment, but is easy to oxidize and volatilize when exposed to light and high temperature, so it needs strict storage conditions[2]. It is easy to store and transport when following the storage requirements, meeting the storage and transportation requirements of industrial production, especially for food, feed and pharmaceutical applications[2][5].
- Multi-functional and Versatile: It integrates multiple biological activities such as antibacterial, antioxidant, lipid-regulating, immune-enhancing, liver-protecting and anti-tumor, with prominent effects on inhibiting bacteria, scavenging free radicals, regulating blood lipids and enhancing body immunity[1][3][7]. It also has effects on anti-parasitic, anti-thrombotic and anti-inflammatory, with strong adaptability in multiple fields and a wide range of application scenarios[1][3]. It is suitable for clinical medical auxiliary, daily health care, food preservation and animal feeding, and can also be used as a natural food additive and feed additive[2][5].
3. Functions
- Broad-Spectrum Antibacterial: As a natural "broad-spectrum antibiotic", its core active component allicin and organic sulfides can effectively inhibit or kill a variety of bacteria, fungi, viruses, amoebas and trichomonads[1][3]. It has obvious inhibitory effects on Staphylococcus, Streptococcus, Escherichia coli, Shigella, Salmonella, Mycobacterium tuberculosis and other bacteria, as well as fungi causing lung and digestive tract infections, and can be used to assist in relieving bacterial and fungal infections[1][3]. The sulfide structure in allicin can combine with the sulfhydryl group in cysteine necessary for bacterial growth and reproduction, inhibiting the activity of sulfhydryl protease and damaging the bacterial cell membrane system[1].
- Powerful Antioxidant: Allicin, garlic polysaccharides and flavonoids in the extract have strong antioxidant activity, which can effectively scavenge DPPH, ABTS+ and other free radicals in the body, inhibit the production of reactive oxygen species (ROS), and reduce oxidative damage to cells and tissues[1][6]. It can also inhibit lipid peroxidation, protect cell membranes from free radical damage, delay the aging process of the body, and has a good auxiliary effect on anti-aging and skin care[1][7].
- Lipid-Regulating and Cardiovascular Protection: Organic sulfides in the extract can regulate lipid metabolism, inhibit the activity of cholesterol synthase, reduce serum cholesterol, triglyceride and lipoprotein content, and reduce the deposition of lipids in blood vessels[1][7]. It can also inhibit platelet aggregation, prevent thrombosis, dilate blood vessels, reduce myocardial oxygen consumption, protect ischemic myocardium, and have an auxiliary improvement effect on hypertension, arteriosclerosis and other cardiovascular diseases[1][3].
- Immune-Enhancing: Garlic polysaccharides and trace elements (selenium, zinc) in the extract can promote the proliferation of lymphocytes, enhance the activity of immune cells, improve the body's resistance to pathogens, and help maintain the body's normal immune function[7]. It can enhance the body's antiviral ability, especially has a certain auxiliary effect on preventing and relieving influenza in high-incidence seasons[7].
- Liver-Protecting: It has a good protective effect on the liver, can regulate immune function, prevent liver damage induced by concanavalin A (Con A), inhibit liver fibrosis, and reduce liver cell damage[1]. It can also promote liver metabolism, assist in relieving liver discomfort, and have an auxiliary improvement effect on chronic liver diseases[1].
- Additional Functions: It has anti-tumor potential, can inhibit the proliferation of various cancer cells (esophageal cancer, gastric cancer, liver cancer, colon cancer, etc.), induce cancer cell apoptosis, block the cancer cell growth cycle, and inhibit cancer cell metastasis[1][4]. It also has anti-parasitic activity, can kill vaginal trichomonads and pinworms, and has an auxiliary effect on relieving parasitic infections[1][3]. In addition, it can improve feed palatability, promote animal digestion and absorption of nutrients, and enhance animal growth performance when used as a feed additive[2][5].
4. Application Fields
- Pharmaceutical Industry: As a core raw material, it is mainly used in the development of drugs for antibacterial, anti-inflammatory, lipid-regulating and liver-protecting. It is also used in pharmaceutical preparations such as oral tablets and capsules for the auxiliary treatment of bacterial and fungal infections (lung and digestive tract fungal infections, bacillary dysentery, tuberculosis, etc.), cardiovascular diseases, liver diseases and parasitic infections[1][3]. Its high-purity allicin is widely used in the research and development of antibacterial and anti-inflammatory drugs, with broad application prospects in the field of medicine[2][4].
- Healthcare Products Industry: Used as a functional ingredient in oral health supplements such as capsules, tablets, oral liquids, health wines and powders, focusing on functions such as antioxidant, lipid-regulating, immune-enhancing and liver-protecting[1][7]. It is especially suitable for middle-aged and elderly people, people with high blood lipid and cardiovascular health needs, people with low immunity, and those who need daily anti-aging care. It should be noted that people with gastric ulcer and hyperacidity should use it with caution[1][7].
- Food Industry: Used as a natural food additive and functional ingredient in functional beverages, health wines, nutritional snacks, edible powders and condiments[2][4]. Its unique garlic flavor can enrich the flavor of food, and its antibacterial and antioxidant properties can extend the shelf life of food, which is suitable for the development of functional health foods focusing on lipid-regulating and immune-enhancing[1][2].
- Feed Industry: Approved as a feed additive, it is used in feed premixes for livestock, poultry and aquatic products[5]. It can improve feed palatability, promote animal digestion and absorption, enhance animal immunity, prevent animal intestinal infections, improve animal growth performance, and has no drug residues and drug resistance[2][5]. It is widely used in poultry breeding, aquaculture and other fields[2][5].
- Other Fields: Applied to antibacterial and soothing skin care products such as facial creams, lotions and disinfectants[1]. Its antibacterial and anti-inflammatory properties can relieve skin inflammation, inhibit the growth of skin bacteria, and have a certain soothing effect on acne-prone skin[1][7]. It can also be used in the research and development of pharmaceutical auxiliary materials and food preservatives, and has broad application prospects in the fields of agriculture, biomedicine and daily chemicals[2][4]. In addition, it can be developed into characteristic health products combining natural plant extracts with modern processing technology, meeting the market demand for natural and safe antibacterial and lipid-regulating ingredients[1][4].
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